Very nice for a first script.
My only suggestions would be:
1.) Use Option Explicit
-It forces you to Dim your variables, and helps promote good coding practices
2.) Don't use On Error Resume Next unless you have to.
-It hides any error messages that might be needed for debugging/troubleshooting
3.) Try condensing your code a little.
-It makes it easier to read, and easier to maintain. For example, if you wanted to run all of your commands in the background, with no windows, with your original script, you would have to change the ,1,true to ,0,true about 7 times. With the below script, just change it in one place.
Option Explicit
'Only use On Error Resume Next when absolutely necessary
'On Error Resume Next
'define our variables
Dim flag_debug, CommandShell, cmdline, oCmdDic
'enable debug mode?
'This is apparently used to just echo back the commandline you are using for each software uninstall.
flag_debug = 0
'create a command shell for use below
Set CommandShell = createobject("wscript.shell")
'create a dictionary object to hold your data pairs
Set oCmdDic = CreateObject("Scripting.Dictionary")
'using a dictionary allows you to add additional software packages with little to no recoding required.
'oCmdDic.Add "Package name", "uninstall commandline"
oCmdDic.Add "WinRAR (fs)", chr(34) & "%ProgramFiles%\WinRAR\Uninstall.exe" & chr(34) & " /s"
oCmdDic.Add "SpyBotSnD (fs)", chr(34) & "%ProgramFiles%\Spybot - Search & Destroy\unins000.exe" & chr(34) & " /SILENT"
oCmdDic.Add "Spy Sweeper (fs)", chr(34) & "%ProgramFiles%\Webroot\Spy Sweeper\unins000.exe" & chr(34) & " /SP- /VERYSILENT /NORESTART"
oCmdDic.Add "Skype (fs)", chr(34) & "%ProgramFiles%\Skype\Phone\unins000.exe" & chr(34) & " /SILENT /NORESTART /SUPPRESSMSGBOXES"
oCmdDic.Add "Partition Magic 8 (msiexec)", "msiexec /X {6BE2A4A4-99FB-48ED-AE1E-4E850389F804} /qn"
oCmdDic.Add "Ad-Aware (msiexec)", "msiexec /X {78CC3BAB-DE2A-4FB4-8FBB-E4DADDC26747} /qn"
oCmdDic.Add "Norton Ghost 2003 (9) (msiexec)", "msiexec /X {3C759736-8347-4031-BB9C-D75ADFE6B1013} /qn /norestart"
'Iterate through each of the packages listed, running the same commands for each package
For Each cmdline In oCmdDic.Items
If flag_debug = 1 Then WScript.Echo cmdline
CommandShell.Run cmdline, 1, True
Next
"Would you like to touch my monkey?" - Dieter (Mike Meyers)
"It is better to die like a tiger, than to live like a pussy."
-Master Wong, from Balls of Fury